Why Is Tamsulosin Taken At Night? - [] 2024: Perú

Contents

- 0.0.1 Is it better to take tamsulosin at night or in the morning?
0.1 Does tamsulosin work better at night?
0.2 Why do I have to wait 30 minutes after a meal to take tamsulosin?

1 Does tamsulosin make you pee more or less?
- - 1.0.1 How many hours does tamsulosin last?
  - 1.0.2 Can I eat 1 hour after taking tamsulosin?
2 What not to do when taking tamsulosin?
- - 2.0.1 Is it OK to take tamsulosin every day?
3 What are the long term effects of taking tamsulosin?
4 Is tamsulosin a lifetime medication?
5 Is tamsulosin a high risk medication?
- 5.1 Can I take tamsulosin 0.4 mg twice a day?
- 5.2 What happens if you take tamsulosin on an empty stomach?
  - 5.2.1 Can tamsulosin affect bowel movements?
6 What not to do when taking tamsulosin?
- - 6.0.1 Can I take tamsulosin 0.4 mg twice a day?
- 6.1 How to take Tamsulosin (FLOMAX) | What All Patients Need to Know | Dose, Side Effects & More
  - 6.1.1 What happens if you take tamsulosin on an empty stomach?
7 Is it OK to take tamsulosin every day?

Is it better to take tamsulosin at night or in the morning?

How to take it – Take your tamsulosin capsules or tablets with a drink of water while either sitting or standing. Swallow them whole. Do not break, chew or crush them. If you can, take tamsulosin in the morning, after breakfast or the first meal or snack of the day.

Does tamsulosin work better at night?

Conclusion: In contrast to other alpha-blockers, night-time dosing is not necessary to improve the tolerability or efficacy of tamsulosin.

Why do I have to wait 30 minutes after a meal to take tamsulosin?

You should take tamsulosin (Flomax) 30 minutes after the same meal every day to ensure that your body absorbs the right amount of medication. Taking it on an empty stomach can cause your body to absorb too much of the medication, which raises your risk of side effects.

Does tamsulosin make you pee more or less?

Descriptions – Tamsulosin is used to treat men who have symptoms of an enlarged prostate gland, which is also known as benign enlargement of the prostate (benign prostatic hyperplasia or BPH). Benign enlargement of the prostate is a problem that can occur in men as they get older.

The prostate gland is located below the bladder. As the prostate gland enlarges, certain muscles in the gland may become tight and get in the way of the tube that drains urine from the bladder. This can cause problems in urinating, such as a need to urinate often, a weak stream when urinating, or a feeling of not being able to empty the bladder completely.

Tamsulosin helps relax the muscles in the prostate and the opening of the bladder. This may help increase the flow of urine or decrease the symptoms. However, tamsulosin will not shrink the prostate. The prostate may continue to get larger. This may cause the symptoms to become worse over time.

Capsule

How many hours does tamsulosin last?

Because of absorption rate-controlled pharmacokinetics with Flomax® (tamsulosin hydrochloride) capsules, the apparent half-life of tamsulosin hydrochloride is approximately 9 to 13 hours in healthy volunteers and 14 to 15 hours in the target population.

Can I eat 1 hour after taking tamsulosin?

How does tamsulosin work? Tamsulosin is a type of medicine known as an alpha blocker (or alpha-adrenoreceptor antagonist). If you have an enlarged prostate gland it helps by relaxing the muscle around the bladder and prostate gland, making it easier to pee.

In some cases it can also be used to help ease the passing of kidney stones through the urinary tract.
Are there any long-term side effects? Tamsulosin is generally safe to take for a long time.
In fact, it works best when you take it for a long time.
What will happen if I stop taking it? Stopping tamsulosin suddenly can make your condition worse as your symptoms may return.

Talk to a doctor if you want to stop taking tamsulosin. If you’re bothered by side effects, the doctor may be able to prescribe a different medicine. If you stop taking tamsulosin, it will take 2 to 3 days for it to be completely out of your body. How does tamsulosin compare with other medicines for enlarged prostate? There are a few other medicines that can help with symptoms of an enlarged prostate.

There are other alpha blockers such as alfuzosin, doxazosin, terazosin, indoramin and prazosin.
Other medicines for enlarged prostate are 5-alpha-reductase inhibitors, also known as dihydrotestosterone inhibitors – for example finasteride and dutasteride.
Some people may need to take a combination of an alpha blocker and a 5-alpha-reductase inhibitor if a single medicine is not helping their symptoms.

Will I need to stop taking tamsulosin before surgery? If you’re going to have cataract or glaucoma surgery, tell the doctor that you’re taking tamsulosin in advance. The doctor may advise you to stop taking tamsulosin 1 or 2 weeks before surgery. This is because tamsulosin may cause complications during the cataract or glaucoma operation.

For any other surgery, ask the nurse or doctor at your pre-assessment appointment if you need to stop taking tamsulosin.
Will it affect my contraception? Tamsulosin does not affect any type of contraception, including the combined pill and emergency contraception,
Will it affect my sex life? Tell a doctor or pharmacist if you are taking medicines for erectile dysfunction (impotence) such as sildenafil, tadalafil or vardenafil.

You may find that tamsulosin makes you feel dizzy or light-headed. If you’re having problems with your sex life after taking tamsulosin, talk to a doctor. Can I drive or ride a bike? Tamsulosin can make you feel dizzy or light-headed, especially when you first start taking it.

If this happens to you, do not drive, cycle or use machinery or tools until you feel better. It’s an offence to drive a car if your ability to drive safely is affected. It’s your responsibility to decide if it’s safe to drive. If you’re in any doubt, do not drive. Talk to your doctor or pharmacist if you’re unsure whether it’s safe for you to drive while taking tamsulosin.

GOV.UK has more information on the law on drugs and driving, Can I drink alcohol while taking tamsulosin? Drinking alcohol can increase the blood pressure-lowering effect of tamsulosin, which can make you feel dizzy or light-headed. During the first few days of taking tamsulosin, it’s best to stop drinking alcohol until you see how the medicine affects you.

If you find taking tamsulosin makes you feel dizzy, it’s best to stop drinking alcohol.
Is there any food or drink I need to avoid? During the first few days of taking tamsulosin, it’s best not to drink alcohol until you see how the medicine affects you.
Other than that, you can eat and drink normally while taking tamsulosin.

It’s important to take tamsulosin after breakfast. If you do not eat breakfast, take your medicine after your first meal or snack of the day. Can lifestyle changes help symptoms of an enlarged prostate gland? Making some simple changes to your lifestyle can help with symptoms of an enlarged prostate gland,

Drink fewer fizzy drinks and less alcohol, caffeine and artificial sweeteners – they can irritate the bladder and make urinary symptoms worse. Quit smoking – nicotine can irritate the bladder and make urinary symptoms worse.Drink less in the evening – try to reduce the amount you drink and avoid drinking anything for 2 hours before bedtime. This might help you avoid getting up in the night. Make sure you’re still drinking enough fluids earlier in the day.Empty your bladder – remember to go to the toilet before long journeys or other situations when you know you may not be able to reach a toilet easily.Try double voiding – wait a few moments after you have finished peeing, then try to go again. It can help you empty your bladder properly (but take care not to strain or push).Check your medicines – ask a doctor whether any medicines you take, such as antidepressants or decongestants, may be making your urinary symptoms worse.Eat more fruit and fibre – this can help you avoid constipation, Being constipated can put pressure on the bladder and make your symptoms worse.

Page last reviewed: 2 February 2023 Next review due: 2 February 2026

What not to do when taking tamsulosin?

Uses – Read the Patient Information Leaflet if available from your before you start taking this and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this medication by as directed by your doctor, usually once daily, 30 minutes after the same meal each day.

Swallow this medication whole.
Do not crush, chew, or open the capsules.
The dosage is based on your medical condition and response to treatment.
May cause a sudden drop in your, which could lead to or,
This risk is higher when you first start taking this drug, after your doctor increases your dose, or if you restart treatment after you stop taking it.

During these times, avoid situations where you may be injured if you faint. Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. If you have not taken this drug for several days, contact your doctor to see if you need to be restarted at a lower dose.

Is it OK to take tamsulosin every day?

INTRODUCTION – Benign prostatic hyperplasia (BPH) describes a common condition in old age in which there is a benign enlargement of the prostate gland. BPH may lead to bladder outlet obstruction, initially inducing lower urinary tract symptoms (LUTS).

About 70% of men under the age of 80 years are affected by LUTS. LUTS include storage and voiding, the severity of which can be assessed using the International Prostate Symptom Score (IPSS). BPH can be treated using surgical therapies, for example, transurethral resection of the prostate or medical therapies (e.g., α1-Adrenoceptor antagonists, 5α-reductase inhibitors, or a combination).

However, α-blockers are the drugs of choice for LUTS secondary to BPH (LUTS/BPH). Alpha 1-adrenoceptor is additionally divided into three subtypes α 1a, α 1b, and α 1d, α 1a being the most predominant in patient with BPH (up to 85%). Alpha-blockers relax prostatic smooth muscles thus relieving LUTS/BPH.

Uroselective drugs, such as tamsulosin, that specifically target α 1a-receptors have an advantage over the other less selective α-blockers, especially in reducing serious side effects such as hypotension.
Due to their high selectivity, these drugs have low-cardiovascular side effects and virtually no intervention with the activity of antihypertensive agents.

Tamsulosin (0.4 mg) daily proved to be favorably safe, effective, and well-tolerated. However, tamsulosin is known to cause ejaculatory dysfunction. This side effect has a significant impact on the patients’ quality of life. Several studies were conducted to assess the efficacy of modified dosage of tamsulosin into either lowering the dose (0.2 mg) or using it intermittently to alleviate ejaculatory issues, showed a potential improvement for the medication’s overall effectiveness.

What are the long term effects of taking tamsulosin?

If you’ve been prescribed tamsulosin (brand name Flomax) for benign prostatic hyperplasia (BPH), you might want to know more about potential tamsulosin side effects. Although studies show that tamsulosin is a safe and effective medication, all drugs can have the potential for adverse effects.

Some tamsulosin side effects include dizziness, headaches, priapism, low blood pressure, and more.
Continue reading to learn more about the medication.
Tamsulosin (brand name Flomax) is part of a class of medications known as alpha-blockers (α-blockers).
The medication is FDA-approved to treat benign prostatic hyperplasia (BPH), also known as an enlarged prostate.

This is a common condition that affects about half of all men between the ages of 51 and 60 and over 70% of men older than 60. The prostate gland is located at the base of the bladder and surrounds the ureter (the tube that carries urine from the bladder out of the body via the penis ).

As the prostate gets larger, it can put pressure on the urethra, leading to lower urinary tract symptoms (LUTS).
A classic symptom of BPH is needing to pee more often, especially at night.
Other symptoms of BPH include difficulty starting urination, weak urine flow, straining when urinating, and starting/stopping frequently during urination.

Tamsulosin helps relax the muscles of the prostate and bladder. This can allow the urethra to expand and improve the flow of urine, alleviating urinary symptoms caused by an enlarged prostate. Other examples of alpha blockers include prazosin (brand name Minipress), silodosin (brand name Rapaflo), alfuzosin (brand name Uroxatral), terazosin (brand name Hytrin), and doxazosin (brand name Cardura).

Dizziness or lightheadedness
Headache
Runny nose, stuffy nose, or other “common cold” symptoms
Abnormal ejaculation, such as ejaculation failure
Drowsiness
Diarrhea
Intraoperative floppy iris syndrome (can occur during cataract surgery or glaucoma surgery)

Serious side effects of tamsulosin can include:

Chest pain (angina)
Low blood pressure or fainting (syncope), especially when standing from a sitting position (also known as orthostatic hypotension)
A severe allergic reaction with skin rash, swelling, and trouble breathing; if you have a history of an allergy to sulfonamide (“sulfa”) drugs, you may also have an allergic reaction to tamsulosin

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Tamsulosin also has potential drug interactions with several different medications, including PDE5 inhibitors used to treat erectile dysfunction and drugs that block the liver enzymes needed to break down tamsulosin. Let your healthcare provider know if you’re taking any other medications, whether over-the-counter or prescription drugs.

In the last few years, there’s been some controversy about whether tamsulosin increases the risk of dementia in the elderly. A 2018 study examined Medicare data about men taking tamsulosin over a period of six years (2006-2012). The researchers found that taking tamsulosin may increase the risk of developing dementia.

However, a 2019 study pointed out several limitations of the study mentioned above. Using records from the National Health Insurance Database, South Korean researchers looked for a connection between α-blocker use and dementia inKorean adults with BPH between 2011 and 2017—they didn’t find one.

The authors concluded that benign prostatic hyperplasia medication is not associated with a risk of dementia. It does not seem that tamsulosin definitively increases the risk of dementia in the elderly, but more research is needed. A study looking at the long-term safety and effectiveness of tamsulosin in men who took tamsulosin for six years found that some of the most common adverse effects included infection, accidental injury, runny nose, pain, and sore throat.

Other reported side effects included abnormal ejaculation, syncope, and orthostatic hypotension. Interestingly, participants’ side effects declined over the six-year period, with the highest levels occurring in the first two years of treatment. In summary, people taking tamsulosin to treat BPH urinary symptoms continued to have safe and well-tolerated relief of their symptoms for up to six years.

If you stop taking tamsulosin (brand name Flomax) for a few days, talk with a healthcare provider before starting again.
Your provider may have you restart at the lowest dose to prevent side effects.
If you experience any symptoms of BPH, it’s important to make an appointment with your healthcare provider as soon as possible.

They will help you develop a safe and effective treatment plan to relieve your symptoms. If you have any medical questions or concerns, please talk to your healthcare provider. The articles on Health Guide are underpinned by peer-reviewed research and information drawn from medical societies and governmental agencies.

American Urology Association (AUA). (2021). Urology Care Foundation: What is benign prostatic hyperplasia? Retrieved from https://www.urologyhealth.org/urologic-conditions/benign-prostatic-hyperplasia-(bph)
Duan, Y., Grady, J.J., Albertsen, P.C., et al. (2018). Tamsulosin and the risk of dementia in older men with benign prostatic hyperplasia. Pharmacoepidemiology and Drug Safety, 27 (3), 340–348. Retrieved from https://doi.org/10.1002/pds.4361. Retrieved from https://pubmed.ncbi.nlm.nih.gov/29316005/
DailyMed. (2021). Tamsulosin hydrochloride capsule. Retrieved from https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=339c3b57-a339-4578-bfd7-46b25d911ff6
Narayan, P. & Tunuguntla, H.S. (2005). Long-term efficacy and safety of tamsulosin for benign prostatic hyperplasia. Reviews in Urology, 7 Suppl 4 (Suppl 4), S42–S48. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1477608/
Tae, B., Bum Sik Tae Department of Urology, Jeon, B., et al. (2019). α-Blocker and risk of dementia in patients with benign prostatic hyperplasia: a nationwide population based study using the national health insurance service database. The Journal of Urology, 202 (2), 362–368. doi:10.1097/JU.0000000000000209Retrieved from https://www.auajournals.org/doi/10.1097/JU.0000000000000209

Dr. Chimene Richa is a board-certified Ophthalmologist and Senior Medical Writer/Reviewer at Ro.

Can I drink coffee after taking tamsulosin?

Tamsulosin tablets. Tamsulosin for enlarged prostate

Take one tablet/capsule every day. Your first dose of tamsulosin may make you feel dizzy or faint, or start sweating. Take your first dose at bedtime and remain lying down until these symptoms have completely passed. Tamsulosin can cause dizziness which may affect your ability to drive. Make sure your reactions are normal before you drive and before you use tools or machines.

table>

Type of medicine An alpha-blocker Used for Enlargement of the prostate gland in men Also called Cositam®; Contiflo®; Faramsil®; Flomax® Relief; Flomaxtra®; Losinate®; Omsula®; Pamsvax®; Petyme®; Tabphyn®; Tamfrex®; Tamsumac®; Tamurex® Combination brands : Combodart®; Dutrozen®; (tamsulosin with); Vesomni® (tamsulosin with ) Available as Prolonged-release tablets and capsules

The prostate gland commonly becomes larger in older men. The prostate is situated close to the bladder, so its enlargement can cause problems with passing urine. Common symptoms that are experienced are having to wait before your urine starts to flow, taking longer at the toilet, dribbling urine, and a feeling that your bladder is not quite empty.

Tamsulosin works by relaxing the muscles around your bladder and prostate gland so that you can pass urine more easily.
Sometimes, more than one type of medicine is needed to control the symptoms of prostate enlargement.
Tamsulosin is available in combination with other medicines for prostate enlargement.

The combination brand called Combodart® contains tamsulosin with a medicine called, and the combination brand called Vesomni® contains tamsulosin with a medicine called, These brands may give better relief of symptoms than tamsulosin alone. Tamsulosin is also available from pharmacies as a medicine called Flomax® Relief.

The pharmacist will need to ask a number of questions about your medical history to make sure that tamsulosin is suitable for you.
You will also need to be diagnosed by your doctor as having an enlarged prostate gland.
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken.

For these reasons, before you start taking tamsulosin it is important that your doctor or pharmacist knows:

If you ever feel dizzy or faint when you stand up, or if you have ever fainted after passing urine.If you need to have cataract eye surgery.If you have any problems with the way your liver works, or any problems with the way your kidneys work.If you have ever had an allergic reaction to a medicine.If you are taking or using any other medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines.

Before you start the treatment, read the manufacturer’s printed information leaflet from inside the pack. It will give you more information about tamsulosin and will provide you with a full list of the side-effects which you may experience from taking it.Take tamsulosin exactly as your doctor or pharmacist tells you to. Swallow each dose with a drink of water – do not crush, break, or chew the tablets/capsules.Your first dose of tamsulosin may make you feel dizzy or faint, so it is important that you take it just before you go to bed. If you feel dizzy or weary, or if you start sweating, remain lying down until these symptoms have completely gone.Take one tablet/capsule every day. After the first dose, you can take your dose at a time of day that best suits you. Although you can take tamsulosin either before or after a meal, the usual advice is to take your doses after the same meal of the day each day. If you forget to take a dose, take it as soon as you remember. If you do not remember until the following day, skip the forgotten dose. Do not take two doses at the same time to make up for a missed dose.

Tamsulosin can cause dizziness particularly when you first start taking it. This may affect your ability to drive. Make sure your reactions are normal before you drive or do things which would be dangerous if you were not fully alert.Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. Your doctor may want to take your blood pressure from time to time, particularly when you first start the treatment.You are advised not to drink alcohol while you are on tamsulosin. Alcohol increases the risk of side-effects from tamsulosin, such as feeling faint or dizzy.Consider reducing or stopping the amount of caffeine you drink (commonly found in tea, coffee and cola). Caffeine can make your symptoms worse, so drinking less of these things may benefit you.If you are a smoker, stopping smoking may significantly improve your symptoms. This is because nicotine irritates the bladder. You can ask your doctor for advice on quitting.If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking tamsulosin. This is because your blood pressure may drop suddenly if you have an anaesthetic. If you are having cataract surgery, it is particularly important that you tell your surgeon you are on tamsulosin. This is because an eye problem known as ‘floppy iris syndrome’ has developed in some people and your doctor may advise you to stop taking tamsulosin for a short while.

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with tamsulosin. You will find a full list in the manufacturer’s information leaflet supplied with your medicine.

Common tamsulosin side-effects (these affect fewer than 1 in 10 men)	What can I do if I experience this?
Feeling dizzy	Do not drive and do not use tools or machines while affected
Ejaculation problems	If this becomes troublesome, speak with your doctor for advice

If you experience any other symptoms which you think may be due to tamsulosin, speak with your doctor or pharmacist for further advice.

Keep all medicines out of the reach and sight of children.Store in a cool, dry place, away from direct heat and light.

Never take more than the prescribed dose. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty. If you buy any medicines, always check with a pharmacist that they are safe to take alongside your prescribed medicines. This medicine is for you. Never give it to other people even if their condition appears to be the same as yours. Do not keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you. If you have any questions about this medicine ask your pharmacist.

Tamsulosin tablets. Tamsulosin for enlarged prostate

What happens if you take tamsulosin with food?

INTRODUCTION – Benign prostate hyperplasia (BPH) is one of the common diseases in aging males, affecting nearly half of men aged over 50 years and nearly 90% of men over 80 years in general populations, The most common complication of BPH is acute urinary retention that diminishes quality of life.

However, sometimes BPH can lead to more severe complications such as urinary tract infections, formation of bladder stones and damage to the bladder wall and kidneys,
The medical treatments with alpha-blockers or 5-alpha-reductase inhibitors are first-line therapy for the medical treatment of BPH at present,

Alpha-blockers relax the smooth muscles of the prostate, therefore improving urinary flow and low urinary tract symptoms, Tamsulosin, a first subtype-selective alpha-1 antagonist, is one of the preferred alpha- blockers due to its relatively lower rate of adverse events (AEs) compared with other alpha-blockers,

Tamsulosin is known to exhibit linear pharmacokinetic (PK) characteristics between 0.1 to 1.0 mg,
The majority of the absorbed tamsulosin is distributed in the extracellular fluids of the body and mostly metabolized by hepatic enzymes such as CYP3A4 and CYP2D6,
The oral absorption of tamsulosin hydrochloride (HCl) has been known to be food-sensitive.

When tamsulosin is administered with food, the absorption rate and the maximum plasma concentration (C max ) are decreased compared to its administration in the fasted state. However, the overall plasma exposure of tamsulosin, represented by the area under the plasma concentration-time curve (AUC), is similar regardless of food intake,

To decrease the C max related AEs, such as orthostatic hypotension, it is recommended tamsulosin be administered after a meal as per the drug label,
The standard treatment regimen of tamsulosin for BPH is different between Western and Asian countries, and the difference in body weight between ethnic groups is one of the reasons for it,

Currently, a initial daily dose of 0.4 mg tamsulosin is recommended in western countries. In some Asian countries, such as Korea and China, a lower dose (0.2 mg) is initially used, and the dose is titrated according to the patients’ drug responses, However, the clinical evidence for using 0.2 mg tamsulosin as a standard regimen for the treatment of BPH in Asian population is insufficient, and 0.4 mg tamsulosin was more effective than 0.2 mg tamsulosin for the initial medication therapy of BPH in several recent studies conducted in Korea,

For these reasons, Hanmi Tams Caps.0.4 mg (Hanmi Pharmaceutical Co., Seoul, Korea), a tamsulosin 0.4 mg formulation, was developed for the initial treatment of BPH for improving medical adherence.
Based on these understandings, the purpose of the present study was to evaluate the PK characteristics including the effect of food on the oral bioavailability and tolerability profile of a novel tamsulosin 0.4 mg formulation.

Moreover, this study also aimed to compare the PK characteristics and tolerability of novel tamsulosin 0.4 mg formulation versus the existing tamsulosin 0.2 mg formulation in healthy male subjects at fed states.

Does tamsulosin cause frequent urination at night?

Tamsulosin reduces nighttime urine production in benign prostatic hyperplasia patients with nocturnal polyuria: a prospective open-label long-term study using frequency-volume chart. Neurourol Urodyn.

Can enlarged prostate go back to normal?

What can I expect if I have benign prostatic hyperplasia? – The outlook for people with BPH is very good. BPH doesn’t have a cure, but treatments can help alleviate your symptoms. Mild symptoms may not require treatment. Medications, surgery and minimally invasive treatments can treat more severe cases.

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Does tamsulosin make you harder?

Tamsulosin as a selective alpha-blocker with the effect on prostate and corporal smooth muscle can cause the smooth muscles to relax and minimize resistance to incoming blood flow into the penis, thereby causing penile erection.

Does tamsulosin damage the kidneys?

Warnings – Tamsulosin oral capsules may not be right for you or contraindicated if you have certain medical conditions or other factors that affect your health. Talk with your doctor about your health history before you take tamsulosin oral capsules. Factors to consider include those in the list below.

Severe kidney or liver problems. Your kidneys and liver clear tamsulosin from your body after you take a dose. If you have severe kidney or liver problems, your body might not be able to properly clear the drug. This can cause levels of it to build up, increasing your risk for side effects. If you have kidney or liver problems, your doctor will recommend if tamsulosin is safe for you to take. People with mild or moderate kidney or liver problems are usually able to take this drug. Sulfa allergy. If you’re allergic to sulfa drugs, you may not be able to take tamsulosin. In rare cases, you may have a severe allergic reaction that’s life threatening. Your doctor can give you more information about the safety of tamsulosin use if you have a sulfa allergy, Allergic reaction. If you’ve had an allergic reaction to tamsulosin or any of its ingredients, tamsulosin oral capsules are contraindicated for you. You should not take tamsulosin oral capsules, because doing so could put you at serious risk for harmful side effects. Ask your doctor what other medications are better options for you. Low blood pressure. Tamsulosin can cause orthostatic hypotension, which is a drop in your blood pressure that happens when you change positions. This can cause dizziness, fainting, and lightheadedness. If you already have low blood pressure, you may have a higher risk for this side effect with tamsulosin. This effect is more likely during the first few weeks of tamsulosin treatment or whenever your dose of the drug is changed. Your doctor can provide more information about this side effect and how to manage it. Planned cataract or glaucoma surgery. If you’re planning to have surgery for cataracts or glaucoma, taking tamsulosin can increase certain risks related to the surgeries. The drug can increase risks both during and after surgery. You may also have a higher risk for these problems if you’ve taken tamsulosin in the past, even if you’re no longer taking it. Check with your doctor and eye doctor before having any eye surgeries. If you have a surgery planned, your doctor will likely have you wait to start tamsulosin until sometime after your surgery. Prostate cancer. Before you start treatment with tamsulosin, your doctor will check to see if you have prostate cancer, They’ll also routinely monitor you for signs of prostate cancer during your treatment with tamsulosin.

Is it better to take tamsulosin once or twice a day?

Dosing – The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

For oral dosage form (capsules):

For benign prostatic hyperplasia:

Adults—At first, 0.4 milligram (mg) once a day. Your doctor may increase your dose if needed. Children—Use is not recommended.

Is tamsulosin a lifetime medication?

Discussion – The long-term efficacy of medical therapy in BPH is measured by the durability of clinical response, patient satisfaction over several years, and the rate of secondary intervention (eg, surgery) for acute urinary retention. Four long-term trials of pharmacologic treatment of BPH have been published to date.

Of α-blockers marketed in the United States for treating BPH for extended periods, doxazosin, 19 terazosin, 20 and tamsulosin 10 have all been demonstrated to be effective. The study by Narayan and colleagues is the longest to date, with up to 6 years’ treatment of patients with tamsulosin. The results of the long-term study by Narayan and associates demonstrate that patients with LUTS due to BPH who are treated with tamsulosin continue to have sustained relief of symptoms for up to 6 years, with excellent safety and tolerability profiles and without development of tolerance.

The study confirmed the outcomes found in previous short-term clinical trials.5 – 7 Adverse events (whether or not related to treatment) occurred more frequently during the first 2 years of treatment and diminished with continuation of therapy. In addition, the rates of discontinuation due to adverse events in the study were low over the course of 4–6 years and consistent with previous experience with tamsulosin.5 – 7 The overall incidence of new TEAEs has shown progressive decline over 6 years.

Is tamsulosin a high risk medication?

The bottom line. Overall, tamsulosin is a safe medication for BPH. But certain side effects may be concerning in older adults. In particular, dizziness and orthostatic hypotension may raise your risk of falling, which could result in fractures.

Can I take tamsulosin 0.4 mg twice a day?

SPL PATIENT PACKAGE INSERT – Tamsulosin Hydrochloride Capsules (tam-SOO-loe-sin HIGH-droe-KLOR-ide) Read the Patient Information that comes with tamsulosin hydrochloride capsules before you start taking it and each time you refill your prescription. The information may have changed.

This leaflet does not take the place of discussions with your doctor about your medical condition or your treatment. What are tamsulosin hydrochloride capsules? Tamsulosin hydrochloride capsules are a prescription alpha-blocker medicine used to treat the signs and symptoms of benign prostatic hyperplasia (BPH), a condition your doctor may refer to as an enlarged prostate.

• Tamsulosin hydrochloride capsules are not for women. • Tamsulosin hydrochloride capsules are not for children. Who should not take tamsulosin Hydrochloride capsules? Do not take tamsulosin hydrochloride capsules if you are allergic to any of its ingredients.

See the end of this leaflet for a complete list of ingredients in tamsulosin hydrochloride capsules.
What should I tell my doctor before using tamsulosin hydrochloride capsules? Before taking tamsulosin hydrochloride capsules, tell your doctor about all your medical conditions, including: • any kidney or liver problems.

• any history of low blood pressure. • any allergies to sulfa or any other medicines.

• if you are planning to have cataract or glaucoma surgery.
Tell your doctor about all the medicines you take, including:

• any prescription medicines, including blood pressure medicines. • any non-prescription medicines, including vitamins and herbal supplements. Some of your other medicines may affect the way tamsulosin hydrochloride capsules work. Especially tell your doctor if you take a medicine for high blood pressure.

You should not take tamsulosin hydrochloride capsules if you are already taking certain blood pressure medicines.
Now the medicines you take.
Eep a list of them and show it to your doctor and pharmacist when you get a new medicine.
How should I take tamsulosin hydrochloride capsules? • Take tamsulosin hydrochloride capsules exactly as prescribed by your doctor.

• Do not crush, chew, or open tamsulosin hydrochloride capsules. • Take tamsulosin hydrochloride capsules one time each day, about 30 minutes after the same meal each day. For example, you may take tamsulosin hydrochloride capsules 30 minutes after dinner each day.

• If you take more tamsulosin hydrochloride capsules than prescribed, call your doctor right away.
What are the possible side effects of tamsulosin hydrochloride? Possible side effects of tamsulosin hydrochloride capsules may include:

• Decreased blood pressure when changing positions, Tamsulosin hydrochloride capsules may cause a sudden drop in blood pressure upon standing, especially after the first dose or when changing doses. Symptoms may include: • fainting • dizziness • lightheadedness Change positions slowly from lying down to sitting up or from a sitting to a standing position until you learn how you react to tamsulosin hydrochloride capsules.

Rare and more serious allergic reactions may also occur. Get medical help right away if you have any of the following reactions: • swelling of face, tongue, or throat
• blistering of the skin

• difficulty breathing • A painful erection that will not go away, Tamsulosin hydrochloride capsules can cause a painful erection (priapism), which cannot be relieved by having sex. If this happens, get medical help right away. If priapism is not treated, you may not be able to get an erection in the future.

Common side effects of tamsulosin hydrochloride capsules may include: • runny nose • dizziness
• decreased semen

These are not all the possible side effects with tamsulosin hydrochloride capsules. Tell your doctor if you have any side effect that bothers you or that does not go away. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088, or by visiting www.fda.gov/medwatch What should I avoid while taking tamsulosin hydrochloride capsules? Avoid driving, operating machinery, or other dangerous activities, until you know how tamsulosin hydrochloride capsules affects you.

Tamsulosin hydrochloride capsules may cause a sudden drop in blood pressure upon standing, especially after the first dose or when changing doses.
See “What are the possible side effects of tamsulosin hydrochloride capsules?” How do I store tamsulosin hydrochloride capsules? Store tamsulosin hydrochloride capsules at room temperature 68°F to 77°F (20°C to 25°C).

Short-term exposure to higher or lower temperatures is acceptable. Ask your doctor or pharmacist if you have any questions about storing your capsules. Keep tamsulosin hydrochloride capsules and all medicines out of the reach of children. General information This medicine was prescribed for you by your doctor for your condition.

Do not use it for another condition.
Do not give tamsulosin hydrochloride capsules to other people, even if they have the same symptoms that you have.
It may harm them.
While taking tamsulosin hydrochloride capsules, you must have regular checkups.
Follow your doctor’s advice about when to have these checkups.

BPH can occur with other more serious conditions, including prostate cancer. Therefore, ask your doctor about screening for prostate cancer prior to treatment with tamsulosin hydrochloride capsules and at regular intervals afterwards. This patient information leaflet summarizes the most important information about tamsulosin hydrochloride capsules.

If you would like more information, talk with your doctor. You can ask your pharmacist or doctor for information about tamsulosin hydrochloride capsules that is written for health professionals. For more information call 1-888-943-3210. What are the ingredients in tamsulosin hydrochloride capsules? • Active Ingredient: tamsulosin hydrochloride • Inactive Ingredients: polysorbate 80, methacrylic acid copolymer dispersion, triacetin, sodium lauryl sulfate, microcrystalline cellulose and calcium stearate.

The capsule shells have the following inactive ingredients: FD & C Blue 2, iron oxide black, iron oxide red, iron oxide yellow, titanium dioxide and gelatin. The black ink have the following inactive ingredients: shellac, propylene glycol, black iron oxide E172 and potassium hydroxide.

What happens if you take tamsulosin on an empty stomach?

You should take it with food whenever possible. If you take tamsulosin on an empty stomach, tamsulosin levels can rise rapidly in your bloodstream. This can lead to more side effects, like headache or dizziness. It’s recommended to take the medication 30 minutes after the same meal each day.

Can tamsulosin affect bowel movements?

Tamsulosin induced diarrhea: a case report Department of Pharmacology, Government Medical College, Bhavnagar, Gujarat, 364001, India Find articles by Sir T General Hospital, Bhavnagar, Gujarat, India Find articles by Sir T General Hospital, Bhavnagar, Gujarat, India Find articles by Department of Pharmacology, Government Medical College, Bhavnagar-364001, Gujarat, India Find articles by Tamsulosin is a uroselective α 1A adrenergic receptor blocker used for benign prostatic hyperplasia with lower urinary tract symptoms. Other α 1 blockers (nonselective subtypes) include prazosin, terazosin, and doxazocin. As per one large-scale study, dizziness, abnormal ejaculation, headache, hypotension, gastrointestinal disorder, nausea, cardiovascular disorder, impotence, and dry mouth are frequent side effects associated with tamsulosin. The reported frequency of diarrhea with tamsulosin is 0.1–1% is lower compared with prazosin (<4%), terazosin (4%) and doxazosin (1–3%). Clinicians favor tamsulosin in the treatment of benign prostatic hyperplasia due to its uroselective action as well as the reduced cardiovascular and gastrointestinal side effects. Herewith, we report a case of tamsulosin-induced diarrhea. A 52-year-old male patient visited the surgical outpatient department of Sir Takhtsinhji General Hospital, Bhavnagar, India with complaints of pain during micturition and increased frequency of urine for 5 months. Ultrasonography findings showed right kidney size 88 × 46 mm (normal), left kidney size 107 × 55 mm, with tiny calculous in upper calyx, prostate size 34 × 39 × 35 mm, volume 26 ml and postvoidal residual volume (PURV) of 65 ml. Urine routine microscopy and routine blood investigations were within the normal values. The patient was diagnosed with benign prostatic hyperplasia with urinary tract infection and was prescribed a tablet of tamsulosin 0.4 mg daily, a tablet of norfloxacin 400 mg twice a day, omeprazole 20 mg twice a day, as well as ibuprofen 400 mg and dicyclomine 10 mg every 8 h for 7 days. On taking the first dose of prescribed medications, he developed watery diarrhea with a frequency of 5–6 times per day. The patient took oral rehydration solution (ORS) but diarrhea did not recover. Tamsulosin was withdrawn on the third day while the other medication was continued. The frequency of diarrhea decreased and he recovered within 2 days of stopping the drug. As the patient's urinary symptoms did not improve, tamsulosin 0.4 mg was prescribed again after 7 days. Following re-administration of tamsulosin, the patient redeveloped watery diarrhea within 24 h. The patient was given ORS and tamsulosin was continued. Diarrhea gradually improved within 7 days and was not reported thereafter. Tamsulosin was continued for 2.5 months after which the patient underwent visual internal urethrotomy. The patient did not have hypertension, diabetes, allergies or similar events. Moreover, there was no change in his regular diet pattern during and before the course of the event. The patient's written informed consent was obtained during extensive history taking. Diarrhea is a common side effect of many drugs. In the present case, the patient received tamsulosin, norfloxacin, omeprazole and ibuprofen, which can commonly cause diarrhea. Culture and viral polymerase chain reaction investigations of stool were not performed to rule out the infective diarrhea; however, the temporal relationship and positive de-challenge and re-challenge confirmed tamsulosin as the culprit drug. As per the Naranjo causality assessment scale, diarrhea was probably related to tamsulosin (score 8) whereas according to the World Health Organization causality assessment scale, the relationship between diarrhea and tamsulosin was probable. Sympathetic stimulation in the gastrointestinal system causes intestinal relaxation (α 1 and β 2 receptors effect) and constriction of the sphincter (α 1 receptor effect). The blockade of the α 1 receptor results in increased peristaltic movement with relaxation of the sphincter that causes diarrhea. Diarrhea is reported with selective α 1 blockers whereas, the nonselective α blocker phenoxybenzamine is found useful for nonresponsive diarrhea in animals. Among selective α 1 blockers, the incidence of diarrhea is found less with a uroselective α 1 blocker. The differences in incidence of diarrhea with different α receptor blockers can be due to differences in α subtype receptor specificity. The α 1 receptors have three different subtypes: α 1A, α 1B and α 1D. The internal anal sphincter has α 1A and α 1D receptors which cause its constriction. However, which α 1 subtype exists in intestinal smooth muscle is not clear. The lower incidence of diarrhea with tamsulosin as compared with a nonselective subtype α 1 blocker (prazosin) may be due to lack of its effect on intestinal smooth muscle. Moreover, the tone of the internal anal sphincter reduces with age that may also contribute to diarrhea. In the present case, the patient developed diarrhea within 24 h of re-administration of tamsulosin and recovered within 7 days even though the course was continued. This suggests that the patient could have developed a tolerance to this side effect. Clinicians should keep this side effect in mind when prescribing tamsulosin and the patient should be informed about this side effect as well as the possibility of developing a tolerance to the drug. Funding: This research received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors. Conflict of interest statement: The authors declare that there is no conflict of interest. Arunkumar D. Rana, Department of Pharmacology, Government Medical College, Bhavnagar, Gujarat, 364001, India. Kinjal Dodiya, Sir T General Hospital, Bhavnagar, Gujarat, India. Manish J. Barvaliya, Government Medical College, Bhavnagar, Gujarat, India. Sameer Shah, Sir T General Hospital, Bhavnagar, Gujarat, India. Bhargav M. Purohit, Department of Pharmacology, Government Medical College, Bhavnagar-364001, Gujarat, India. Chandrabhanu Rajkishor Tripathi, Government Medical College, Bhavnagar, Gujarat, India.1. Wilde MI, McTavish D. Tamsulosin. A review of its pharmacological properties and therapeutic potential in the management of symptomatic benign prostatic hyperplasia, Drugs 1996; 52 : 883–898.2. Michel MC, Bressel HU, Goepel M, et al. A 6-month large-scale study into the safety of tamsulosin, Br J Clin Pharmacol 2001. Jun; 51 : 609–614.3. FLOMAX CR Product Monograph. BoehringerIngelheim (Canada) Ltd,, (accessed 4 May 2017).4. Prazosin Side Effects in Detail - Drugs.com, Available at: (accessed 4 May 2017).5. Terazosin Side Effects in Detail - Drugs.com, Available at: (accessed 4 May 2017).6. Doxazosin Side Effects in Detail - Drugs.com, Available at: (accessed 4 May 2017).7. Hood DM, Stephens KA, Bowen ML. Phenoxybenzamine for the treatment of severe nonresponsive diarrhoea in the horse, J Am Vet Med Assoc 1982; 180 : 758–762.8. Owaki H, Sadahiro S, Takaki M. Characterizations of the α1-adrenoceptor subtypes mediating contractions of the human internal anal sphincter, J Pharmacol Sci 2015; 127 : 424–429. Articles from Therapeutic Advances in Drug Safety are provided here courtesy of SAGE Publications : Tamsulosin induced diarrhea: a case report

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What not to do when taking tamsulosin?

Swallow this medication whole. Do not crush, chew, or open the capsules. The dosage is based on your medical condition and response to treatment. may cause a sudden drop in your, which could lead to or, This risk is higher when you first start taking this drug, after your doctor increases your dose, or if you restart treatment after you stop taking it.

Can I take tamsulosin 0.4 mg twice a day?

This leaflet does not take the place of discussions with your doctor about your medical condition or your treatment. What are tamsulosin hydrochloride capsules? Tamsulosin hydrochloride capsules are a prescription alpha-blocker medicine used to treat the signs and symptoms of benign prostatic hyperplasia (BPH), a condition your doctor may refer to as an enlarged prostate.

See the end of this leaflet for a complete list of ingredients in tamsulosin hydrochloride capsules. What should I tell my doctor before using tamsulosin hydrochloride capsules? Before taking tamsulosin hydrochloride capsules, tell your doctor about all your medical conditions, including: • any kidney or liver problems.

How to take Tamsulosin (FLOMAX) | What All Patients Need to Know | Dose, Side Effects & More

• any history of low blood pressure. • any allergies to sulfa or any other medicines.

• if you are planning to have cataract or glaucoma surgery.
Tell your doctor about all the medicines you take, including:

You should not take tamsulosin hydrochloride capsules if you are already taking certain blood pressure medicines. Know the medicines you take. Keep a list of them and show it to your doctor and pharmacist when you get a new medicine. How should I take tamsulosin hydrochloride capsules? • Take tamsulosin hydrochloride capsules exactly as prescribed by your doctor.

• If you take more tamsulosin hydrochloride capsules than prescribed, call your doctor right away.
What are the possible side effects of tamsulosin hydrochloride? Possible side effects of tamsulosin hydrochloride capsules may include:

Rare and more serious allergic reactions may also occur. Get medical help right away if you have any of the following reactions: • swelling of face, tongue, or throat
• blistering of the skin

Common side effects of tamsulosin hydrochloride capsules may include: • runny nose • dizziness
• decreased semen

Tamsulosin hydrochloride capsules may cause a sudden drop in blood pressure upon standing, especially after the first dose or when changing doses. See “What are the possible side effects of tamsulosin hydrochloride capsules?” How do I store tamsulosin hydrochloride capsules? Store tamsulosin hydrochloride capsules at room temperature 68°F to 77°F (20°C to 25°C).

Do not use it for another condition. Do not give tamsulosin hydrochloride capsules to other people, even if they have the same symptoms that you have. It may harm them. While taking tamsulosin hydrochloride capsules, you must have regular checkups. Follow your doctor’s advice about when to have these checkups.

If you would like more information, talk with your doctor.
You can ask your pharmacist or doctor for information about tamsulosin hydrochloride capsules that is written for health professionals.
For more information call 1-888-943-3210.
What are the ingredients in tamsulosin hydrochloride capsules? • Active Ingredient: tamsulosin hydrochloride • Inactive Ingredients: polysorbate 80, methacrylic acid copolymer dispersion, triacetin, sodium lauryl sulfate, microcrystalline cellulose and calcium stearate.

What happens if you take tamsulosin on an empty stomach?

Is it OK to take tamsulosin every day?

About 70% of men under the age of 80 years are affected by LUTS.
LUTS include storage and voiding, the severity of which can be assessed using the International Prostate Symptom Score (IPSS).
BPH can be treated using surgical therapies, for example, transurethral resection of the prostate or medical therapies (e.g., α1-Adrenoceptor antagonists, 5α-reductase inhibitors, or a combination).

Uroselective drugs, such as tamsulosin, that specifically target α 1a-receptors have an advantage over the other less selective α-blockers, especially in reducing serious side effects such as hypotension. Due to their high selectivity, these drugs have low-cardiovascular side effects and virtually no intervention with the activity of antihypertensive agents.